Nuclc. Acids. Res. OUP
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Biomolecular Interaction Network Database (BIND)

http://bind.ca

Bader, G.D.2, Donaldson, I.5, Wolting, C.5, Ouellette, B.F.F.3, Pawson, T.2, Hogue, C.W.V.2

2Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada M5G 1X5
3Centre for Molecular Medicine and Therapeutics, Children and Women's Health Centre of British Columbia, University of British Columbia, Vancouver, Canada V5Z 4H4
5MDS Proteomics, Inc. 251 Attwell Drive Toronto, Canada M9W 7H4

Contact   gary.bader@utoronto.ca


Database Description

The Biomolecular Interaction Network Database (BIND: http://bind.ca) archives biomolecular interaction, complex and pathway information. A web-based system is available to query and view the information. BIND continues to grow with the addition of individual submissions as well as interaction data from the PDB and a number of large-scale interaction and complex mapping experiments using yeast two hybrid, mass spectrometry, genetic interactions, and phage display. We have developed a new graphical analysis tool that provides users with a view of the domain composition of proteins in interaction and complex records to help relate functional domains to protein interactions. An interaction network clustering tool has also been developed to help focus on regions of interest. Continued input from users has helped further mature the BIND data specification, which now includes the ability to store detailed information about genetic interactions.

Recent Developments

A new web-based graphical tool for viewing the domains of proteins in the context of interactions and complexes will soon be available.

Category   Intermolecular Interactions

Go to the abstract in the NAR 2003 Database Issue.

 

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