Go to the abstract in the NAR 2002 Database Issue.
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http://www.ens-lyon.fr/LBMC/laudet/nurebase.html
Duarte, J.1, Ourjdal, T.1, Perriere, G.2, Laudet, V.1, Robinson-Rechavi, M.1
1Laboratoire de Biologie Moléculaire et Cellulaire UMR CNRS 5665 Ecole Normale Supérieure de Lyon 46, allée d'Italie 69364 LYON cédex 07 France
2Laboratoire de Biométrie et Biologie Évolutive UMR CNRS 5558 Université Claude Bernard - Lyon 1 43, bd. du 11 Novembre 1918 69622 Villeurbanne Cedex France
Contact marc.robinson@ens-lyon.fr
Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and annotations for all nuclear receptors. The reviewed NUREBASE is completed by NUREBASE_DAILY, automatically updated every 24 hours. Both databases are organized under a client/server architecture, with a client written in Java which runs on any platform. This client, named FamFetch, integrates a graphical interface allowing selection of families, and manipulation of phylogenies and alignments. NUREBASE sequence data is also accessible through a World-Wide Web server, allowing complex queries. All information on accessing and installing NUREBASE may be found at http://www.ens-lyon.fr/LBMC/laudet/nurebase.html.
NUREBASE version 2 includes standardized names for coding sequences, with annotation of alternative transcripts. Expression patterns deduced from EST data are represented by standardized keywords for human; extension to other species is under progress.
NUREBASE is supported by the CNRS.
Category Protein Databases
Go to the abstract in the NAR 2002 Database Issue.