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Full-Malaria

http://fullmal.ims.u-tokyo.ac.jp

Watanabe, J.¹, Sasaki, M.², Suzuki, Y.², Sugano, S.²

¹Department of Parasitology, Institute of Medical Science, The University of Tokyo
²Laboratoty of Genome Structure Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo

Contact   jwatanab@manage.ims.u-tokyo.ac.jp

Database Description

We made a full-length enriched cDNA library from the erythrocytic stage parasites of Plasmodium falciparum 3D7 strain, the causative agent of the lethal malaria in humans. One pass reading of 5�f end revealed that about 50% of clones contain the complete protein-coding sequence and considered full. Database consists of determined sequence data, which can be searched using BLAST or with keywords. Start sites of the redundant clones were dispersedly distributed, suggesting that it is a general rule in this organism. With the completion of whole genome sequencing, this library will be useful for correct annotation of the expressed genes.

Recent Developments

Sequenced plasmid have been deposited at MR4.

Acknowledgements

This database is maintained by a grant-in-Aid for Publication of Scientific Research Results from Japan Society for the Promotion of Science.

REFERENCES

Watanabe J, Sasaki M, Suzuki Y, Sugano S. (2001)
FULL-malaria: a database for a full-length
enriched cDNA library from human malaria
parasite, Plasmodium falciparum. Nucleic Acid
Res. 29, 70-71.
Watanabe J, Sasaki M, Suzuki Y, Sugano S. (2002)
Analysis of transcriptomes of human malaria
parasite Plasmodium falciparum using full-length
enriched library: identification of novel genes
and diverse transcription start sites of
messenger RNAs. Gene 291, 105-113.

Category   Genomic Databases

Go to the abstract in the NAR 2001 Database Issue.