Nuclc. Acids. Res. OUP
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MitBASE

http://www3.ebi.ac.uk/Research/Mitbase/mitbase.pl

Contact   marcella@area.ba.cnr.it


Database Description

MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects under a single interface databases for plant, vertebrate, invertebrate, human, protist, and fungal mtDNA. It also contains a pilot database on nuclear genes involved in mitochondrial biogenesis in S. cerevisiae. MitBASE reports all available information from different organisms and from intraspecies variants and mutants. Data have been drawn from the primary databases and from the literature; value-added information has been structured, e.g. editing information on protist mtDNA genomes, pathological information for human mtDNA variants, etc. Ad hoc retrieval systems have been devised for some of the above listed databases keeping into account their peculiarities. The impact of this project is intended for both basic and applied research. The study of mitochondrial genetic diseases and mitochondrial DNA intraspecies diversity are key topics in several biotechnological fields. The database has been funded within the EU Biotechnology programme (IV Framework Programme). The MitBASE database is at present no more updated due to lack of funding. The change of the ORACLE DBMS release at the EBI does not allow the retrieval of the data because no computer scientist is available for the software updating. Human MitBASE Database, the database of human mitochondrial DNA variants related to population and clinical studies is available through SRS at the following address http://bighost.area.ba.cnr.it/mitochondriome .

Acknowledgements

none

Category   Genomic Databases

Go to the abstract in the NAR 2000 Database Issue.

 

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