Nuclc. Acids. Res. OUP
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MitoNuc/MitoAln

http://bio-www.ba.cnr.it:8000/BioWWW/#MitoNuc

Attimonelli, M.1, Catalano, D.1, Gissi, C.2, Grillo, G.3, Licciulli, F.1, Liuni, S.3, Pesole, G.2, Saccone, C.1

1Dipartimento di Biochimica e Biologia Molecolare, Università di Bari, via E. Orabona 4, 70126 Bari, Italy
2Dipartimento di Fisiologia e Biochimica Generali, Università di Milano, via Celoria 26, 20122 Milano, Italy
3Centro di Studio sui Mitocondri e Metabolismo Energetico C.N.R., via Amendola 166/5, 70126 Bari, Italy

Contact   marcella@area.ba.cnr.it


Database Description

Mitochondria, besides their central role in energy metabolism, have been recently found to be involved in a number of basic processes of cell life and to contribute to the pathogenesis of many degenerative diseases. All functions of mitochondria depend on the interaction of nuclear and organellar genomes. Mitochondrial genomes have been extensively sequenced and analyzed collecting data in several specialized databases. In order to collect information on nuclear coded mitochondrial proteins we developed MitoNuc and MitoAln, two related databases containing respectively detailed information on sequenced nuclear genes coding for mitochondrial proteins in Metazoa and yeast, and the multiple alignments of the relevant homologous protein coding regions. MitoNuc and MitoAln retrieval through SRS at http://bio-www.ba.cnr.it: 8000/srs6/ can easily allow to extract sequence data, subsequences defined by specific features and nucleotide or aminoacid multiple alignments.

Category   Genomic Databases

Go to the abstract in the NAR 2002 Database Issue.

 

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