Go to the abstract in the NAR 2003 Database Issue.
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National Center for Biotechnology Information NLM/NIH Bldg. 38A Rm 6N605 8600 Rockville Pike Bethesda, MD 20894 USA
Contact pruitt@ncbi.nlm.nih.gov
RefSeq provides curated non-redundant sequence standards for genomic regions, transcripts (including splice variants), and proteins. Three pipelines support this effort: the annotation pipeline provides automatic computationally derived RefSeqs which complement the manual curation effort. Two pipelines (Entrez Genomes and LocusLink) welcome collaborations with the research community and are subject to in-house manual curation. The RefSeq collection supports genome annotation, gene characterization, mutation analysis, expression studies, and polymorphism discovery.
The collection has been expanded to include non-coding transcripts (such as structural or functional RNAs and pseudogenes). The collection makes available over 440,000 proteins from the three pipelines.
RefSeq and LocusLink: NCBI gene-centered resources.
Pruitt KD, Maglott DR
Nucleic Acids Res 2001 Jan 1;29(1):137-140
Introducing RefSeq and LocusLink: curated human genome resources at the NCBI.
Pruitt KD, Katz KS, Sicotte H, Maglott DR
Trends Genet. 2000 Jan;16(1):44-47.
Category Varied Biomedical Content
Go to the abstract in the NAR 2003 Database Issue.