Go to the abstract in the NAR 2003 Database Issue.
 |
 |
|||||||
|
||||||||
Contact gelbart@morgan.harvard.edu
FlyBase (http://flybase.bio.indiana.edu/) provides an integrated view of the fundamental genomic and genetic data on the major genetic model Drosophila melanogaster and related species. FlyBase has primary responsibility for the continual reannotation of the D. melanogaster genome. The ultimate goal of the reannotation effort is to decorate the euchromatic sequence of the genome with as much biological information as is available from the community and from the major genome project centers. A complete revision of the annotations of the now-finished euchromatic genomic sequence has been completed. There are many points of entry to the genome within FlyBase, most notably through maps, gene products and ontologies, structured phenotypic and gene expression data, and anatomy.
Re-evaluation of the Drosophila melanogaster euchromatic genome has been completed, with major improvements to the annotation based on a finished high-quality genomic sequence, a vastly increased cDNA and EST collection, and the enormously increased set of genomic and protein sequences now available. The changes to the genome annotations have been incorporated into the FlyBase dataset and are accessible through revised gene reports and annotation browsing/querying tools. Annotation efforts will continue, relying on comparative data from other insect genomes including Drosophila pseudoobscura, Anopheles gambiae and Apis mellifera, and on continual expansion of the reference cDNA set, the DGC (Drosophila Gene Collection) and will expand to include other sequence features in addition to gene models.
Category Genomic Databases
Go to the abstract in the NAR 2003 Database Issue.